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The authors concluded that probiotic and prebiotic supplementation exerts measurable antioxidant and anti-inflammatory effects in this model, supporting their potential as complementary neuroprotective strategies ( Supplementation with three different lactobacillus strains to VPA-induced ASD mice improved behavioral symptoms compared to the risperidone group, a drug approved by the Food and Drug Administration

On the second day, for all the groups, the different compounds were administered via oral gavage after 1-hour fasting, followed by the choline chloride load the next hour

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Hortelano S, Dallaporta B, Zamzami N, Hirsch T, Susin SA, Marzo I, et al