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Description

These bispecific ADCs are significantly superior to monoclonal anti-EGFR or anti-B7-H3 ADCs and have a lower toxicity profile [463]

VH: variable heavy chain

This paper was one of the first reports on the crucial roles of the interactions between SH3 domains and PRR for the association of p47phox with both p22phox in the membrane and p67phox in the cytosol