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Another study published in Clinical Medicine Insights: Endocrinology and Diabetes found a high prevalence of B12 deficiency in hypothyroid patients, with approximately 40% being deficient

For injections, vitamin D3 is often preferred because its stronger and helps maintain higher vitamin D levels for a longer time

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However, it is worth noting that another medication in the incretin-based therapy class metformin is well-established to reduce vitamin B12 absorption in some patients through effects on calcium-dependent ileal uptake mechanisms