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Human impacts have shaped historical and recent evolution in Aedes aegypti, the dengue and yellow fever mosquito

However, smaller nanoparticles are prone to agglomeration and rapid excretion through the kidneys, evading liver uptake and reducing the circulation time in the body, ultimately diminishing the therapeutic efficacy [20]

Work from our and other groups showed that LAC also modulates acetylation of NF-B/p65 subunit, which potentiates the transcriptional activity of NF-B member to increase transcription of the Grm2 gene encoding for the mGlu2 receptor in hippocampus and prefrontal cortex of FSL rats [30, 36]

We also analysed tissue sections from the olfactory nerve, olfactory bulb, trigeminal nerve and brain (beyond the olfactory bulb) for the presence of C