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Kadia T, Borthakur G , Jabbour E, Konopleva M, Ravandi F, DiNardo C, Zheleva D, Blake D, Chiao J

doi: 10.1038/nature13166 453 KonermannSBrighamMDTrevinoAEJoungJAbudayyehOOBarcenaCet al

In animal models, lithium increased intracellular glutathione levels and reduced oxygen metabolite damage, suggesting that it selectively boosts glutathione-dependent enzymes to protect against free radical stress