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Although there was no significant effect on body weight, BMI, or truncal adiposity, there was a significant decrease in appetite scores and eating behavior [16]

It also helps regulate nitric oxide levels, which improves circulation and reduces oxidative stresstwo key components in healing joint injuries

Notably, increased NAD+ levels also activate NAD+dependent signaling pathways such as sirtuins (SIRT1/SIRT3), further enhancing mitochondrial biogenesis and energy metabolism

These bioactive compounds modulate a variety of molecular targets and physiological pathways, contributing to their anti-inflammatory, antioxidant, mucosal protective, immunomodulatory, and microbiota-modulating effects