alc l-carnitine administrare Raw Acetyl-L-Carnitine L- Carnitine

doi: 10.1371/journal.pone.0241928 107 NagalakshmiB.SagarkarS.SakharkarA

The growing body of evidence linking mitochondrial dysfunction and impaired fatty acid metabolism to HF provides not only mechanistic insights but also translational opportunities for novel interventions

[Abstract]2021 Nov 16;12(12):1084

Due to an ineffective blood-nerve barrier in our peripheral nervous system, exposure to some chemotherapeutic agents causes mitochondrial swelling in peripheral nerves, which lead to the opening of mitochondrial permeability transition pore and cytochrome c release resulting in degeneration of primary afferent sensory fibers