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Key Takeaway Psoriatic arthritis is a whole-body autoimmune condition wearing two faces, one on the skin and one in the joints

Vijay-KumarMAitkenJDCarvalhoFACullenderTCMwangiSSrinivasanSet alMetabolic syndrome and altered gut microbiota in mice lacking toll-like receptor 5

Their main adverse effects, including weight gain and neuropsychiatric symptoms, are not primarily linked to classical mitochondrial pathways (106, 109)