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v.) in the A549 tumor-bearing mouse model, thus providing precise imaging-guided cancer phototherapy (Figure 2E) ( Multimodel Imaging Based on Heptamethine Cyanine7 Given the drawbacks of NIR imaging, the combination of Cy7-based optical imaging with other conventional imaging techniques, such as photoacoustic imaging (PAI), ultrasound imaging (United States), MRI, computed tomography (CT), single photon emission computed tomography (SPECT), and positron emission tomography (PET), is exploited to overcome NIR imaging limitations of spatial resolution, penetration depth, and tissue scattering

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however, exact cutoffs for safe dosing are difficult to determine and are likely subject to factors related to the individual