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This comprehensive study contributes to the continuing efforts of the EPA's Aging Water Infrastructure (AWI) research, the US Conference of Mayors Water Council, and the asset management and water infrastructure condition assessment efforts of the American Water Works Association (AWWA) and American Society of Civil Engineers (ASCE)

In addition, many preclinical and clinical studies have been conducted and are ongoing to explore the antiproliferative, anti-invasive, antiangiogenic, and chemoresistance-modulating properties of antioxidants like Curcumin, Lycopene, and Vitamin C

Take organokines for example, they can release from a multitude of organs and tissues, including the liver (hepatokines), heart (cardiokines), skeletal muscle (myokines), WAT (adipokines), BAT (baptokines), and neurons (neurokines)