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Furthermore, sirtuins have been observed to inhibit the downstream NF-kB signaling pathway of macrophages through TLR4 or RAGE receptors by reducing the release of DAMPs from hepatocyte (Yang et al

Belonging to the Zygophyllaceae family, a diverse and globally distributed group comprising 25 genera and approximately 250 species (Stefanescu et al., 2020)

Funding Statement The author(s) declare that no financial support was received for the research, authorship, and/or publication of this article

We also tested the possibility that cell death results from compensatory hyper-activation and reductive stress response to oxidative stress, which may lead to cell death [74]