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Description

Mitophagy in degenerative joint diseases

Firmness / elasticity via stimulation of collagen & elastin, helps with mild sagging or laxity

doi: 10.1016/j.celrep.2018.10.073 195 ChintaKCPaclHTAgarwalASteynAJC

At the cellular level, transferrin (TF) mediates the cellular uptake of Fe 3+ via endocytosis of iron-loaded TF-bound transferrin receptor 1 (TFR1), followed by release from the endosome, 93,94 in which Fe 3+ is then converted to Fe 2+ via the metalloreductase STEAP3