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Initially, the drug enters cells through the plasma membrane monoamine transporter (PMAT) and organic cation transporter 3 (OCT3) located on the surface of small intestinal epithelial cells

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Growth hormone secretagogues and receptor types Growth hormone releasing peptides illustrate receptor competition clearly

the cleavable linking group is cleaved at least 10 times or more, preferably at least 100 times faster in the target cell or under a first reference condition (which can, e.g., be selected to mimic or represent intracellular conditions) than in the blood of a subject, or under a second reference condition (which can, e.g., be selected to mimic or represent conditions found in the blood or serum)