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In the folate cycle, glycine and serine fuel the mitochondrial enzymes SHMT2, MTHFD2 and ALDH1L2, which play critical roles in the cancer survival and proliferation presumably through purine production

Thus, our research unveils how GSH metabolism regulates redox control, and provides a strong framework for understanding how microbes mitigate harmful radicals released by host phagocytic cells a factor strongly correlated with survival and disease dissemination in the host

Cen et al

(2012) Glutathione precursor N-acetyl-cysteine modulates EEG synchronization in schizophrenia patients: a double-blind, randomized, placebo-controlled trial