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Based on the evidence, fish oil supplementation has favorable effects on autoimmune and inflammatory diseases including lupus erythematosus, psoriasis, inflammatory bowel diseases (IBD), rheumatoid arthritis, and even neuroinflammatory diseases, such as multiple sclerosis (MS) and migraine (127, 130)

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A D-dopachrome converting enzyme was first discovered in mammals (Orlow et al., 1994), which associates with tyrosinase and other enzymes in the pathway to form a melanogenic complex