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Description

The peptide selectively binds copper over other divalent metal ions present in physiological conditions, and the resulting complex is stable across a relevant pH range

Rasmussen H

Assessment of neurological function Global neurological deficits were quantified using the Bederson score (Supplementary Table 10)

Pegvisomant increases the metabolic rate of food-deprived mice To assess whether the energy-conserving effects of GH can be pharmacologically manipulated, we tested in mice the effects of a clinically available GHR antagonist (pegvisomant)