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PMCID: PMC9124646

Ideally, these should be consumed fresh or lightly cooked, as this helps retain their antioxidant properties

Indeed, deletions or mutations of the SHANK3 gene have been found both in patients with PMS, which occur in over 50% of ASD patients [338], and in ASD patients outside the PMS

The copper content of GHK-Cu formulations has been a theoretical safety consideration, given that excessive copper can be toxic - however, the amounts used in cosmetic and research applications are extremely small, the copper is tightly chelated by the peptide (reducing free copper availability), and topical absorption of copper from these products appears minimal and well below levels that would cause systemic copper accumulation or toxicity