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PPIs are prescribed for more severe symptoms

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MTHFR converts 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate and participate in folate and homocysteine conversion correlated to DNA methylation 1

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Angiletta CJ, Griffin LE, Steele CN et al (2018) Impact of short-term flavanol supplementation on fasting plasma trimethylamine N -oxide concentrations in obese adults

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