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doi: 10.3389/fimmu.2025.1509131 Received 10 October 2024 Accepted 19 March 2025 Published 03 June 2025 Volume 16 - 2025 Edited by Carlos Manuel Zapata-Martn del Campo, National Institute of Cardiology Ignacio Chavez, Mexico Reviewed by Robet L

However, developing engineered microbes as live biotherapeutic products presents considerable challenges in regulatory affairs, manufacturing, genetic stability, biocontainment, delivery, engraftment, and overall safety (135)

in contrast to insulin metformin and sulfonylurea, co-prescription has been shown to decrease the mean blood vitamin B 12 level and the prevalence of vitamin B 12 deficiency was significantly increased

The code employed instance segmentation to map out the particle tracks and then used 3d reconstruction with the stereoscopic camera system to visualize the particles in a 3d plane