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doi: 10.3390/ijms22031228 3

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A universal, continuous assay for SAM-dependent methyltransferases

The cultured SGN explants from WT or gpx1 / mice were exposed to peroxynitrite with or without ebselen pretreatment, and the expression changes of 4-HNE were examined to evaluate the oxidative stress level in SGNs (Figure 5A)