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Patients may not require regular transfusions initially but may need them during periods of stress, illness, or physiological demand

*Correspondence: Bonglee Kim, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

FUNDING This work was supported by the by the National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIT) (NRF-2023R1A2C2003479), the Bio&Medical Technology Development Program of the NRF funded by the MSIT (NRF-2019M3E5D3073102), and the Basic Science Research Program funded by the Ministry of Education (NRF-2020R1I1A1A01071665 and RS-2023-00248873)