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In the three-chamber test, MIA mice demonstrated a profound impairment in social interaction, as evidenced by a significantly lower sociability index score of 6.7 1.3, compared to 29.5 1.3 in control mice

That said, its always smart to get them looked at by a board-certified dermatologist, especially if a spot changes shape, color, or starts to itch or bleed. These symptoms can sometimes signal other skin conditionsincluding pre-cancerthat may require medical attention

doi:10.3762/bjoc.4.39

This is particularly true for pigmented macules or patches where the pigment density is variable or where gray or black hues are present