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Conversely, activated astrocytes can secrete BDNF and GDNF to mediate downregulation of DMT1, reducing iron accumulation in neurons [184]

(JCEM 2006) They documented a 2- to 10-fold increase in plasma GH (dose-dependent), a 1.5- to 3-fold increase in IGF-1 for 9-11 days, and a half-life of 5.8 to 8.1 days