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Gerstberger S, Jiang Q, Ganesh K

[7] The reconstituted NAD+ is not preserved for long periods at room temperature, so refrigeration is necessary to slow any breakdown of the product

Following a gradual overload running training (5 days/week, 5 weeks) in mice, the NOX4/H 2 O 2 /NFE2L2 pathway is activated, triggering a range of adaptive responses, including promoting antioxidant defense, enhancing mitochondrial biogenesis, preventing mitochondrial oxidative stress, and maintaining muscle function and exercise capacity, ultimately reducing the onset of insulin resistance associated with ageing and obesity [89]

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