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Studies (42, 43) have shown that apigenin has a pro-apoptotic effect in human RA-FLS, and it can induce RA-FLS apoptosis by mediating ROS and oxidative stress activator ERK1/2, and mediate apoptotic cell death by activating the apoptotic effector caspase-3/7

Studies have shown that vegetarians have low vitamin B blood levels

In addition, this cell line is commonly used to study CBS-mediated hydrogen sulfide (H 2 S) production (Wang et al., 2018), as cystathionine lyase (CSE), the other enzyme involved in H 2 S production, is expressed at very low levels in HepG2 cells

As suggested by phylogenetic inference (Dallinger et al