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It is interesting to note that other post-acute infection syndromes (PAIS) and some neuropsychiatric diseases such as myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), depression (especially the atypical/immunometabolic subtype (IMD) [86]) and others also have fatigue as a leading clinical symptom, which may serve as a model for investigating the mechanisms of fatigue and drawing conclusions regarding therapeutic options in long COVID

The review noted that one study found good results for L-carnitine supplementation for obese subjects, though these effects seemed restricted to the truly obese and were muted in subjects with lower BMIs

Functional neuroimaging biomarkers of resilience in major depressive disorder