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Laminin-5 and MMP upregulation TB4 induces expression of matrix metalloproteinases (MMP-2, MMP-9) that remodel extracellular matrix during healing (Malinda 1999 J Invest Dermatol)

Early attempts included the use of a beta-lactam antibiotic, ceftriaxone, which delayed the disease progression in animal models by upregulating EAAT2/GLT1 [393]

Samples were vortexed again, transferred to GC vials and run directly in a HewlettPackard 7890A gas chromatograph with a 5975C series mass selective detector (column: Agilent DB-5 ms, 60 m 0.25 mm 0.25 m film thickness)

thaliana polyphenolic extract highlight its potential for mitigating AD-like pathologies through inflammation suppression and oxidative stress reduction