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MAD-microbial (origin of) Alzheimers disease hypothesis: from infection and the antimicrobial response to disruption of key copper-based systems

Chen D, Zhang X, Li Z, Zhu B

Almost all polyphenols absorbed in the intestine are transported through the portal vein and undergo phase II metabolism in the liver, forming conjugated polyphenol metabolites that are then transported back to the gastrointestinal tract for further metabolism and/or excreted in the form of feces (Scott et al., 2022)