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Description

Inflammatory cardiomyopathy Myocarditis, an inflammatory CM, is often caused by viruses such as Coxsackie A/B, leading to cardiac dysfunction and remodeling (77, 78)

While not yet approved for general use, they are progressing through late-stage clinical trials and may become an important tool in the near future

The promoter sequence of SIRT5 (chr13: 43,365,384-43,365,730) was obtained from the UCSC Genome Browser ( and inserted into pGL3-Basic Luciferase Reporter Vectors (Promega Corporation, Madison, WI, USA) to construct the wild type (wt) SIRT5 promoter reporter plasmid