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Although low pH in the stomach renders aspirin into its un-ionised, lipid-soluble form, the low surface area of the stomach wall limits the extent of drug absorption

Journal of Pediatric Endocrinology

Heavy coffee consumption (defined in the studies as over 3 cups daily by Europeans, or over 1 cup daily by Japanese) reduced hepatocellular carcinoma (HCC) risk by an average of 55% over 10 observational studies (Bravi 2007