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For example, the binding affinity of the cocaine analog 2-carbomethoxy-3-[4-fluorophenyl]-tropane (CFT) was reduced by almost five fold on hDAT homo-dimer cross-linked with CuP in comparison to the monomeric state (Zhen and Reith, 2018)

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c-Met / proliferation concern is real and unresolved: c-Met is the product of the MET proto-oncogene, and aberrant HGF/c-Met signaling drives several cancers