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The study conducted by Lee and Padgett (2021) with intraarticular injections of BPC-157 did not report any adverse effects, although the screening for adverse events was not discussed at length [34]

Nat Rev Mol Cell Biol 25(1):4664

AnkB-deficient animals have sinus bradycardia, a prolonged QT interval, and other myocardial electrical phenotype changes, promoting myocardial mechanical remodelling as well as premature death, which is related to the low expression of -catenin in the intercalated disc and high expression in the cytoplasm caused by the loss of AnkB