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Description

Manifestations of histamine release and/or peripheral vasodilation may include pruritus, flushing, red eyes, sweating, and/or orthostatic hypotension

Newly developed DAB2IP-targeted strategies, including epigenetic modulators and engineered exosomal circRNA delivery systems, demonstrate preclinical potential but require rigorous validation in various models to assess long-term biosafety and organ-specific efficacy