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5.5 Divergent roles of HO-1 in ferroptosis: between protection and promotion Although numerous studies have suggested that HO-1 may exert neuroprotective effects in VaD by regulating ferroptosis, an in-depth analysis of the existing literature reveals that the findings are not entirely consistent

In FHL124 cells and human lens capsular bags, 30 M resveratrol significantly inhibited cell growth, migration and epithelial-mesenchymal transition (EMT), which are pivotal events for PCO development (109)

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Ginsenosides such as Rg1 and Rd activate Nrf2-driven antioxidant responses in cardiac tissue, leading to higher levels of HO-1 and other antioxidants (Yao et al., 2022)