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The name comes from melas, the Greek word for black, or cholas, from the word green-ish

JZ: Conceptualization, Writingreview and editing

J Biol Chem 2012;287(42):35439-35441

Mechanistically, the inflammatory response after heart transplantation is mediated by TLR4/TRIF signaling pathway, which facilitates neutrophil migration to coronary endothelial cells, resulting in ferroptosis in the transplant endothelial cells