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Research indicates that silibinin can reduce the levels of miRNAs ( miR-125b , miR-182 , and miR-20b ), and up-regulate the levels of pro-apoptotic genes ( p53 , Bax , Caspase-9 , PTEN , and Bcl2L11 ), decrease the level of anti-apoptotic gene ( Bcl-2 ), thereby inducing apoptosis in breast cancer cells (T-47D, MCF-7, and MDA-MB-231) [947, 954]
Crude Protein12% Crude Fat16% Crude Fiber (max)10% Moisture (max)10% Calcium0.2%21 mg Phosphorus0.3%20 mg Potassium1.2%61 mg Magnesium0.5%27 mg Iron1.5 mg Copper0.2 mg Manganese0.3 mg Zinc1.5 mg Iodine0.026 mg Selenium0.005 mg Vitamin A92 IU Vitamin D43 IU Vitamin E10 IU Thiamine (Vitamin B1)0.13 mg Riboflavin (Vitamin B2)0.139 mg Pantothenic acid1 mg Niacin (Vitamin B3)1.7 mg Pyridoxine (Vitamin B6)0.3 mg Folate0.03 mg Vitamin B120.0004 mg Vitamin C*8 mg Vitamin K*0.005 mg Biotin*0.005 mg Chromium*0.009 mg alpha-Amylase (Aspergillus niger) *1965 DU 1 Glucoamylase (Rhizopus) *12 AGU 2 Bromelain (Pineapple Stem) *1160 PU 3 Cellulase (Trichoderma longibrachiatum) *45 CU 4 Hemicellulase (Trichoderma longibrachiatum) *36 HCU 5 Lactase (Aspergillus niger) *161 ALU 6 Lipase (Aspergillus niger) *67 FIP 7 Papain (Papaya) *1160 PU 3 Protease (Aspergillus oryzae) *6516 HUT 8 Guaranteed Analysis per Tablespoon (7g): All guarantees are minimums, unless stated otherwise
Because the strategy lacks platelet-specific functions such as clot retraction and amplification mechanisms driven by platelet secretion, their ability to sustain long-term haemostasis is inherently incomplete, as reflected by occasional rebleeding in the tail-laceration assay (Supplementary Fig
