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Previous work shows that DSIP can inhibit hypoxia-induced reduction of mitochondrial respiratory activity and suggests that DSIPs antioxidant mechanisms could contribute to its neuroprotective effects

In addition, the transpedicular approach caused persistent endplate defects, with Schmorl-like herniations and osseous displacement within the NP

The process of freezing and thawing can create ice crystals that damage the peptides structure, causing aggregation and reducing its bioactivity

This approach helps maintain reproducibility when the compound is integrated into multi-site method development or iterative assay design