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Increasing evidence of astrocyte dysfunction in disease pathology has spurred interest in developing astrocyte-targeted therapeutic strategies (Figure 1, Table 2

Genetic variation in glutathione synthesis genes (GCLC, GCLM) and detoxification pathways (GST polymorphisms) influences baseline glutathione levels and responsiveness to supplementation

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At the same time, it preserved the homeostasis of CD8+ splenocytes, maintaining their cytotoxic function without provoking an excessive inflammatory response [50], suggesting Epitalons role in recalibrating, rather than overactivating, immune function