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The patient felt symptoms but never actually lost consciousness

Kaddurah-Daouk is an inventor on key patents in the field of Metabolomics and hold equity in Metabolon, a biotech company in North Carolina

Following the identification of DEGs, pathway analysis was performed using the SHINYGO web-based tool

In any case, not only ADPR binding but also Ca 2+ binding are prerequisite for TRPM2 channel gating ( N -terminus as a Ca 2+ -binding EF-loop is also critical for hTRPM2 channel activation induced by an unrealistically high concentration (50 mM) of Ca 2+ (Luo et al., 2018)