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Composed of collagen, glycoproteins, proteases, and growth factors, the ECM forms an essential support structure and basis for cellular interactions during tissue regeneration and also serves as a medium between various cells and molecular mediators

Diarrhea and constipation are also commonly observed, each potentially affecting ten to fifteen percent of patients, with individual susceptibility varying based on factors such as baseline gastrointestinal function, dietary habits, and concurrent medications

The formulation and dosage regimens of B12 used to treat Vitamin B12 deficiency vary widely depending on the aetiology of the deficiency as well as region of medical practice (Table 2)

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