glutathione synthetase deficiency testing A rare case of in a newborn with normal neurological development on follow-up Glutathione Pathways

201,202 Previous studies have found that GSDMD is capable of forming pores in the cell membrane, triggering the release of cellular contents and initiating inflammatory responses

These results are not unprecedentedour lab has shown that some RNA viruses target host mRNAs encoding isoforms of thioredoxin reductase via RNA:RNA antisense interactions, which, like proteolysis, would likely also result in host selenoprotein knockdown, but by a different mechanism ( Understanding why RNA viruses may have developed such strategies presents an interesting challenge for future research

doi: 10.1038/s41420-022-01141-y

It assists in the breakdown of glycogen to free up stored glucose for energy