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JTCVS Open 10:296-297, 2022

Investigators tapered or paused doses if intolerance developed (57.4% maintained maximum dose at week 68

Structural insight into the function and anti-TB pro-drug activation by KatG

H (400 MHz, CDCl 3 ): 7.96 (1 H, t, J = 5.6 Hz, NH), 3.63 (2 H, s, SCH 2 ), 3.343.22 (2 H, m, PCH 2 ), 3.18 (2 H, apparent q, J = 5.8 Hz, NCH 2 ), 1.791.66 (2 H, m, CH 2 ), 1.661.56 (2 H, m, CH 2 ), 1.561.44 (2 H, m, CH 2 )