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These are often the first noticeable effects

doi: 10.4103/ipj.ipj_70_18 Beck, A

The main function of protease is to catalyze the hydrolytic reaction that degrades the proteins into peptides and free amino acids so that it prevents the oxidative stress effect on oral tissues

This process is achieved by activating various redox-sensitive kinases (Madamanchi and Runge, 2013), such as protein tyrosine phosphatases (PTPs), controlling phosphorylation-dephosphorylation reactions