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Of note, intracerebroventricular injection of the MOR antagonist naloxone has also been shown to improve opioid-induced constipation 11 , suggesting a role for the brain-gut axis in this condition 12,13

Following uptake, hydrophobic fatty acids do not diffuse freely in the cytosol and must instead be shuttled between different organelles by specific fatty acid binding proteins (FABP) of which FABP1, also known as liver FABP, is the predominant isoform in the liver [13]

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Randomized, placebo-controlled, double-blind trial of Boswellia serrata in maintaining remission of Crohn's disease: good safety profile but lack of efficacy