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Apart from its action on the mitochondria, there is also evidence that Bcl-2 possesses antioxidant property

Progressive growth of infantile cutaneous hemangiomas is directly correlated with hyperplasia and angiogenesis of adjacent epidermis and inversely correlated with expression of the endogenous angiogenesis inhibitor, IFN-beta

A reduction in the levels of GSH, and consequently of antioxidant defenses, may increase the risk of damage to the host via transcription factor activation leading to up-regulation of proinflammatory cytokines, such as nuclear transcription factors and activator proteins, induced in turn by agents such as hydrogen peroxide, mitogens, bacteria, viruses, and UV and ionizing radiation

Comparison of berberine bioavailability between oral and rectal administrations in rats