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If superoxide anions are allowed to accumulate, this can lead to oxidative stress and cell damage

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Together, they generate malignant cell populations with distinct biological properties, evolutionary fitness, and therapeutic sensitivities ( Figure 1 2 Intertumoral and intratumoral heterogeneity: distinct but interconnected dimensions Intertumoral heterogeneity refers to phenotypic and molecular variation between tumors arising in different patients with the same histopathological diagnosis

Change in Erythocyte Glucose 6 phosphate dehydrogenase deficiency (G6PD) and reduced glutathione (GSH) activities in development of senile and diabetic cataracts