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More research is needed to determine future clinical applications in this area

Research into MSA has primarily focused on oligodendroglial and neuronal dysfunction secondary to accumulation of aggregated -synuclein, leading to microglial activation, neuroinflammation and oxidative stress 2,74,75

What New Research Is Saying 1

While T-cell redirection by bispecific antibodies has proven extremely potent, it has also been reported that this initial stimulation over time leads to an exhausted phenotype in the T-cell population causing the anti-tumour effect to subside