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doi: 10.1016/j.ejpb.2011.02.016 74 HazariSAKaurHKarwasraRAbourehabMAKhanAAKesharwaniP

ER stress and UPR are recognized to be important regulators of chondrocyte behaviour, as gene mutations of extracellular matrix proteins or disruption of the UPR pathway result in chondrodysplasia phenotypes 13,14,15,16

The role of ferroptosis in carcinogenesis and cancer therapy is influenced not only by oncogenes and tumor suppressors, but also by the tumor microenvironment (TME) (22)