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Several studies undertaken globally show that women with vitamin B12 deficiency in early pregnancy were up to five times more likely to have a child with neural tube defects, such as spina bifida, compared to women with high levels of vitamin B12

As the resulting lysophospholipid is likely enriched in arachidonic or docosahexaenoic acids, this process may also influence oxylipin production

Boehringer-Mannheim, Mannheim, Germany) for 1015 min

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