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From the results, it is clear that metabolic reprogramming of thyroid nodules, mostly characterized by metabolites, are related to sucrose and glutathione (GSH) metabolism, TCA cycle, FA synthesis, FA beta-oxidation, and nucleotide synthesis

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Additionally, RF arises from diverse etiologies (e.g., diabetic nephropathy, hypertensive nephropathy, and chronic interstitial nephritis), but ferroptosis mechanisms across these etiologies are rarely compared

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